Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:61397
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"A quinoline compound having a cyano group at the 3-position, a 3-chloro-4-(2-pyridylmethoxy)anilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an ethoxy group at the 7-position." []
|
| skos:inScheme | |
| skos:prefLabel |
neratinib
|
| skos:altLabel |
(2E)-N-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
|
| skos:notation |
ChemIDplus:698387-09-6 "CAS Registry Number",
CiteXplore:15715478 "PubMed citation",
KEGG DRUG:D08950 "KEGG DRUG",
Reaxys:9971763 "Reaxys Registry Number"
|
| skos:broader | |
| skos:relatedSynonym |
neratinib,
HKI 272,
N-(4-(3-Chloro-4-(2-pyridinylmethoxy)anilino)-3-cyano-7-ethoxy-6-quinolyl)-4-(dimethylamino)-2-butenamide,
HKI-272,
C30H31ClN6O2,
CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC\\C=C\\CN(C)C,
InChI=1S/C30H31ClN6O2/c1-4-38-29-17-26-24(16-27(29)34-13-7-8-14-37(2)3)30(21(18-32)19-35-26)36-22-10-11-28(25(31)15-22)39-20-23-9-5-6-12-33-23/h5-12,15-17,19,34H,4,13-14,20H2,1-3H3,(H,35,36)/b8-7+,
InChIKey=ZNHPZUKZSNBOSQ-BQYQJAHWSA-N
|