Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:4393
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"A secondary amino compound that is (S)-colchicine in which the N-acetyl group is replaced by an N-methyl group. Isolable from the autumn crocus, Colchicum autumnale, it is less toxic than colchicine and is used as an antineoplastic." []
|
| skos:inScheme | |
| skos:prefLabel |
(-)-demecolcine
|
| skos:altLabel |
(7S)-1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one
|
| skos:notation |
ChemIDplus:477-30-5 "CAS Registry Number",
CiteXplore:1061646 "PubMed citation",
CiteXplore:20082301 "PubMed citation",
CiteXplore:22394737 "PubMed citation",
CiteXplore:2329167 "PubMed citation",
CiteXplore:2977921 "PubMed citation",
CiteXplore:7237451 "PubMed citation",
CiteXplore:7720099 "PubMed citation",
CiteXplore:7887202 "PubMed citation",
KEGG COMPOUND:477-30-5 "CAS Registry Number",
KEGG COMPOUND:C11250 "KEGG COMPOUND",
Patent:DE936268 "Patent",
Reaxys:2822892 "Reaxys Registry Number",
Wikipedia:Demecolcine "Wikipedia"
|
| skos:broader | |
| skos:relatedSynonym |
demecolcine,
(-)-colchamine,
N-methyl-N-desacetylcolchicine,
Colcemid,
N-methyl-N-deacetylcolchicine,
N-desacetyl-N-methylcolchicine,
Santavy's substance F,
Reichstein's F,
demecolcina,
demecolcinum,
N-deacetyl-N-methylcolchicine,
C21H25NO5,
CN[C@H]1CCc2cc(OC)c(OC)c(OC)c2-c2ccc(OC)c(=O)cc12,
InChI=1S/C21H25NO5/c1-22-15-8-6-12-10-18(25-3)20(26-4)21(27-5)19(12)13-7-9-17(24-2)16(23)11-14(13)15/h7,9-11,15,22H,6,8H2,1-5H3/t15-/m0/s1,
InChIKey=NNJPGOLRFBJNIW-HNNXBMFYSA-N
|