Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:3353
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"The 2,3-dihydro-1H-inden-5-yl ester of the active enantiomer of candoxatrilat. Candoxatril is an orally active prodrug of candoxatrilat, a potent neutral endopeptidase (NEP, neprilysin) inhibitor used in the treatment of chronic heart failure." []
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| skos:inScheme | |
| skos:prefLabel |
candoxatril
|
| skos:altLabel |
cis-4-{[(1-{(2S)-3-(2,3-dihydro-1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl}cyclopentyl)carbonyl]amino}cyclohexanecarboxylic acid
|
| skos:notation |
Beilstein:8374063 "Beilstein Registry Number",
ChemIDplus:123122-55-4 "CAS Registry Number",
DrugBank:DB00616 "DrugBank",
KEGG DRUG:D01070 "KEGG DRUG",
Patent:EP274234 "Patent",
Patent:US5030654 "Patent"
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| skos:broader | |
| skos:relatedSynonym |
candoxatril,
[4(S)-cis]-4-[[[1-[3-[(2,3-dihydro-1H-indeb5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic acid,
4-({1-[(S)-2-(Indan-5-yloxycarbonyl)-3-(2-methoxy-ethoxy)-propyl]-cyclopentanecarbonyl}-amino)-cyclohexanecarboxylic acid,
C29H41NO7,
COCCOC[C@H](CC1(CCCC1)C(=O)N[C@H]1CC[C@H](CC1)C(O)=O)C(=O)Oc1ccc2CCCc2c1,
InChI=1S/C29H41NO7/c1-35-15-16-36-19-23(27(33)37-25-12-9-20-5-4-6-22(20)17-25)18-29(13-2-3-14-29)28(34)30-24-10-7-21(8-11-24)26(31)32/h9,12,17,21,23-24H,2-8,10-11,13-16,18-19H2,1H3,(H,30,34)(H,31,32)/t21-,23-,24+/m0/s1,
InChIKey=ZTWZVMIYIIVABD-OEMFJLHTSA-N
|