Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:168396
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases." []
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| skos:inScheme | |
| skos:prefLabel |
mycophenolic acid
|
| skos:altLabel |
(4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
|
| skos:notation |
Beilstein:318158 "Beilstein Registry Number",
ChemIDplus:24280-93-1 "CAS Registry Number",
CiteXplore:11272311 "PubMed citation",
CiteXplore:15470161 "PubMed citation",
CiteXplore:16629948 "PubMed citation",
CiteXplore:16640327 "PubMed citation",
CiteXplore:17482154 "PubMed citation",
CiteXplore:17498396 "PubMed citation",
CiteXplore:18194117 "PubMed citation",
CiteXplore:18611107 "PubMed citation",
CiteXplore:18996104 "PubMed citation",
CiteXplore:19689217 "PubMed citation",
DrugBank:24280-93-1 "CAS Registry Number",
DrugBank:DB01024 "DrugBank",
KEGG DRUG:24280-93-1 "CAS Registry Number",
KEGG DRUG:D05096 "KEGG DRUG",
PDBeChem:MOA "PDBeChem",
Patent:US4753935 "Patent",
Reaxys:318158 "Reaxys Registry Number",
Wikipedia:Mycophenolic_acid "Wikipedia"
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| skos:broader | |
| skos:relatedSynonym |
mycophenolic acid,
acidum mycophenolicum,
acido micofenolico,
Mycophenolsaeure,
Mycophenolate,
acide mycophenolique,
Micofenolico acido,
(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid,
C17H20O6,
COc1c(C)c2COC(=O)c2c(O)c1C\\C=C(/C)CCC(O)=O,
InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+,
InChIKey=HPNSFSBZBAHARI-RUDMXATFSA-N
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