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SubjectPredicateObjectContext
assay:41573assay:descriptionButyrylcholinesteraselld:chembl
assay:48195assay:descriptionCorticosteroid binding globulinlld:chembl
assay:1assay:descriptionThe compound was tested for the in vitro inhibition of platelet 12-lipoxygenase at a concentration of 30 uMlld:chembl
assay:2assay:descriptionCompound was evaluated for its ability to mobilize calcium in 1321NI cellslld:chembl
assay:4assay:descriptionBinding affinity against A2 adenosine receptor in bovine striatal membranes using [3H]CGS-21680lld:chembl
assay:5assay:descriptionIn vitro cell cytotoxicity against 143-B cell lines(Human osteosarcoma cell line)lld:chembl
assay:6assay:descriptionIn vitro cell cytotoxicity against 143-B cell lines(Human osteosarcoma cell line)lld:chembl
assay:7assay:descriptionCytotoxic Activity was evaluated against 143B (TK-) tumor cellslld:chembl
assay:8assay:descriptionIn vitro cell cytotoxicity was determined against 143B cell linelld:chembl
assay:9assay:descriptionInhibitory activity against tumor osteosarcoma cell line 143B after 72 hr continuous exposure to compoundlld:chembl
assay:10assay:descriptionIn vitro cell cytotoxicity against 143B-LTK cell lines expressed in HSV-1 TKlld:chembl
assay:11assay:descriptionIn vitro cell cytotoxicity against 143B-LTK cell lines expressed in HSV-1 TKlld:chembl
assay:12assay:descriptionIn vitro cell cytotoxicity was determined against 143B-LTK cell linelld:chembl
assay:13assay:descriptionThe compound was tested for minimum inhibitory concentration in Staphylococcus aureus,147N penicillin sensitive Staphylococcus aureuslld:chembl
assay:14assay:descriptionThe compound was tested for minimum inhibitory concentration in Staphylococcus aureus,147N penicillin sensitive Staphylococcus aureuslld:chembl
assay:15assay:descriptionThe compound was tested for minimum inhibitory concentration in Staphylococcus aureus,147N penicillin sensitive Staphylococcus aureuslld:chembl
assay:16assay:descriptionThe compound was tested for minimum inhibitory concentration in Staphylococcus aureus,147N penicillin sensitive Staphylococcus aureuslld:chembl
assay:17assay:descriptionInhibition of cytochrome P450 progesterone 15-alpha hydroxylaselld:chembl
assay:18assay:descriptionConcentration that cause 50% activation of human reticulocyte 15-lipoxygenase (15-HLO)lld:chembl
assay:19assay:descriptionInhibition of partially purified 15-lipoxygenase from human leukocyteslld:chembl
assay:20assay:descriptionInhibitory activity against human reticulocyte 15-lipoxygenase (15-HLO)lld:chembl
assay:22assay:descriptionInhibitory activity against human reticulocyte 15-lipoxygenase (15-HLO)lld:chembl
assay:21assay:descriptionCompound was evaluated for the percent increase in activation concentration of human reticulocyte 15-lipoxygenase (15-HLO)lld:chembl
assay:23assay:descriptionInhibitory activity against human reticulocyte 15-lipoxygenase (15-HLO) ;NI is no inhibitionlld:chembl
assay:24assay:descriptionInhibitory activity against human reticulocyte 15-lipoxygenase (15-HLO); NI is no inhibitionlld:chembl
assay:25assay:descriptionInhibitory concentration against 15-lipoxygenase, by inhibiting 15-HETE production by human umbilical vein endothelial cells (HUVEC) stimulated by calcium ionophore A 23187 at concentration of 10e-5 M.lld:chembl
assay:26assay:descriptionIn vitro inhibitory activity of compound on rabbit reticulocyte 15-lipoxygenaselld:chembl
assay:27assay:descriptionInhibition of rabbit reticulocyte 15-lipoxygenase by compound (30 uM)lld:chembl
assay:28assay:descriptionInhibitory activity against 15-lipoxygenase in rat polymorphonuclear leukocyteslld:chembl
assay:29assay:descriptionInhibitory activity against 15-lipoxygenase was determined obtained from soya beanlld:chembl
assay:30assay:descriptionInhibitory activity against soybean 15-lipoxygenase was evaluatedlld:chembl
assay:31assay:descriptionInhibitory activity against soybean 15-lipoxygenase was evaluated at 100 uMlld:chembl
assay:32assay:descriptionThe compound was tested for the in vitro inhibition of 15-lipoxygenase of soybean at a concentration of 10 uMlld:chembl
assay:33assay:descriptionThe compound was tested for the in vitro inhibition of 15-lipoxygenase of soybean at a concentration of 100 uMlld:chembl
assay:34assay:descriptionCompound was tested in vitro for inhibition of 15-lipoxygenase soybeanlld:chembl
assay:35assay:descriptionCompound at 100 uM was tested in vitro for inhibition of 15-lipoxygenase soybeanlld:chembl
assay:36assay:descriptionInhibition of cytochrome P450 progesterone 16-alpha hydroxylaselld:chembl
assay:37assay:descriptionBinding affinity against bacterial 16S rRNA using mass spectrometry based assaylld:chembl
assay:38assay:descriptionDissociation constant with dimeric 16S rRNA RNA construct Blld:chembl
assay:39assay:descriptionDissociation constant towards 16S rRNA construct Alld:chembl
assay:40assay:descriptionDissociation constant towards 16S rRNA construct Blld:chembl
assay:41assay:descriptionBinding affinity of aminoglycoside to 16S ribosomal RNA A-site in Escherichia colilld:chembl
assay:42assay:descriptionBinding affinity for the 16S ribosomal RNA A-site of Escherichia colilld:chembl
assay:43assay:descriptionInhibitory activity against human placenta 17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD type 2)lld:chembl
assay:51assay:descriptionInhibitory activity against human placenta 17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD type 2)lld:chembl
assay:44assay:descriptionInhibitory constant against human placenta 17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD type 2)lld:chembl
assay:45assay:descriptionThe compound was tested at a concentration of 1 uM for inhibitory activity against 17 beta-hydroxysteroid dehydrogenase from human placental microsomeslld:chembl
assay:46assay:descriptionThe compound was tested at a concentration of 1 uM for inhibitory activity against 17 beta-hydroxysteroid dehydrogenase from human placental microsomeslld:chembl
assay:47assay:descriptionInhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationlld:chembl
assay:48assay:descriptionInhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationlld:chembl
assay:49assay:descriptionPercent inhibition of 17-alpha-hydroxylase/17,20 lyase of rat testes microsomes at 100 uMlld:chembl
assay:50assay:descriptionPercent inhibition of Steroid 17-alpha-hydroxylase/17,20 lyase of rat testes microsomes at 100 uMlld:chembl
assay:52assay:descriptionCompound was tested for the inhibition of 17-beta-hydroxysteroid dehydrogenase type 1(17-beta-HSD type 1)lld:chembl
assay:53assay:descriptionCompound was tested for the inhibition of 17-beta-hydroxysteroid dehydrogenase type 1(17-beta-HSD type 1) at 1 uM concentrationlld:chembl
assay:54assay:descriptionCompound was tested for the inhibition of 17-beta-hydroxysteroid dehydrogenase type 1(17-beta-HSD type 1) at 10 uM concentrationlld:chembl
assay:55assay:descriptionSelectivity ratio of binding affinity towards mu to delta receptors of rat brain membraneslld:chembl
assay:149306assay:descriptionSelectivity ratio of binding affinity towards mu to delta receptors of rat brain membraneslld:chembl
assay:56assay:descriptionCytotoxicity against ovarian cancer cell line (1A-9) of humans was determinedlld:chembl
assay:57assay:descriptionFunctional antagonism by electrical assays in Xenopus oocytes expressing 1A/2A NMDA receptor subtypelld:chembl
assay:58assay:descriptionFunctional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2B NMDA receptorlld:chembl
assay:59assay:descriptionFunctional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2C NMDA receptorlld:chembl
assay:60assay:descriptionIn vitro effective concentration required to reduce the number of human ovarian cancer (1A9) after 3-day incubationlld:chembl
assay:61assay:descriptionIn vitro effective concentration required to reduce the number of human ovarian cancer cells (1A9) after 3-day incubationlld:chembl
assay:62assay:descriptionCytotoxic activity against human ovarian cancer (1A9) cell linelld:chembl
assay:63assay:descriptionCytotoxic activity against human ovarian cancer (1A9) cell line; ND=Not determinedlld:chembl
assay:64assay:descriptionEffective dose of compound against replication of 1A9 cell line was evaluatedlld:chembl
assay:65assay:descriptionIn vitro cytotoxic activity was determined against ovarian cancer (1A9) cell linelld:chembl
assay:66assay:descriptionIn vitro cytotoxicity evaluated against human ovarian cancer (1A9 cell line)lld:chembl
assay:67assay:descriptionIn vitro cytotoxicity evaluated against human ovarian cancer (1A9 cell line); NA is not activelld:chembl
assay:68assay:descriptionIn vitro percent inhibition evaluated against human ovarian cancer (1A9 cell line) at >20 ug/mLlld:chembl
assay:69assay:descriptionInhibitory activity against Taxol resistant 1A9 cell lineslld:chembl
assay:70assay:descriptionCytotoxicity against human ovarian cancer (1A9) cell lines.lld:chembl
assay:71assay:descriptionPercentage inhibition of human ovarian cancer (1A9) cell lines.lld:chembl
assay:72assay:descriptionEffective dose required for inhibitory activity against 1A9 human tumor cell line.lld:chembl
assay:73assay:descriptionPercent inhibition against 1A9 human tumor cell line at 0.10 ug/mLlld:chembl
assay:74assay:descriptionPercent inhibition against 1A9 human tumor cell line at <0.00008 ug/mLlld:chembl
assay:75assay:descriptionPercent inhibition against 1A9 human tumor cell line at >10 ug/mLlld:chembl
assay:76assay:descriptionInhibitory concentration against Jurkat cellslld:chembl
assay:92487assay:descriptionInhibitory concentration against Jurkat cellslld:chembl
assay:77assay:descriptionIn vitro anticancer activity against 2 SCLC cell line; inactivelld:chembl
assay:78assay:descriptionInhibition of cytochrome P450 progesterone 2-alpha-hydroxylaselld:chembl
assay:79assay:descriptionIn vitro inhibition of human 2,3-oxidosqualene cyclase.lld:chembl
assay:80assay:descriptionIn vitro inhibition of human 2,3-oxidosqualene cyclase.lld:chembl
assay:81assay:descriptionIn vitro inhibition of human 2,3-oxidosqualene cyclase at 100 nM.lld:chembl
assay:82assay:descriptionCompound was evaluated for the inhibition of microsomal 2,3-oxidosqualene cyclase in Candida albicans microsomeslld:chembl
assay:83assay:descriptionCompound was evaluated for the inhibition of microsomal 2,3-oxidosqualene-lanosterol cyclase in Candida albicans microsomeslld:chembl
assay:84assay:descriptionCompound was evaluated for the inhibition of microsomal 2,3-oxidosqualene cyclase in Saccharomyces cerevisiae microsomeslld:chembl
assay:85assay:descriptionCompound was evaluated for the inhibition of microsomal 2,3-oxidosqualene-lanosterol cyclase in Saccharomyces cerevisiae microsomeslld:chembl
assay:86assay:descriptionCompound was evaluated for the inhibition of microsomal 2,3-oxidosqualene-lanosterol cyclase in pig liver microsomeslld:chembl
assay:87assay:descriptionConcentration required to inhibit rat liver 2,3-oxidosqualene-lanosterol cyclaselld:chembl
assay:88assay:descriptionConcentration required to inhibit rat liver 2,3-oxidosqualene-lanosterol cyclase (OSC)lld:chembl
assay:89assay:descriptionEvaluated for its activity to inhibit rat liver 2,3-oxidosqualene-lanosterol cyclase, activity expressed as Killd:chembl
assay:90assay:descriptionCompound was evaluated for the inhibition of microsomal 2,3-oxidosqualene cyclase in rat liver microsomeslld:chembl
assay:91assay:descriptionCompound was evaluated for the inhibition of microsomal 2,3-oxidosqualene-lanosterol cyclase in rat liver microsomeslld:chembl
assay:92assay:descriptionCompound was evaluated for inhibitory activity against 2,3-oxidosqualene-lanosterol cyclase in rat liver microsomeslld:chembl
assay:93assay:descriptionMolar concentration needed to give 50% prevention of 2-5A (Adenosine dependent endoribonuclease)lld:chembl
assay:94assay:descriptionMolar concentration required to displace 50% of the radiolabeled probe from 2-5A (Adenosine dependent endoribonuclease) in endonuclease-nitrocellulose complexlld:chembl
assay:95assay:descriptionIn vitro cytotoxic concentration required to inhibit hepatitisB virus (HBV) replication in 2.2.15 cell linelld:chembl
assay:96assay:description50% Effective concentration of compound required for inhibiting intracellular viral replicative intermediate DNA in HBV-transfected 2.2.15 cell line.lld:chembl
assay:97assay:descriptionAntiviral activity against Hepatitis B virus in 2.2.15 cell linelld:chembl
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