APC gene


MSH: Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.,NCI: This gene plays a role in signal transduction. It is involved in both adhesion and migration of cells.

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