| http://linkedlifedata.com/r... | rdf:type | skos:Concept | lld:geneontology |
| http://linkedlifedata.com/r... | skos:definition | "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathways) which typically lead to rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. The process ends when the cell has died. The process is divided into a signaling pathway phase, and an execution phase, which is triggered by the former." [GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263] | lld:geneontology |
| http://linkedlifedata.com/r... | skos:inScheme | lld:geneontology | lld:geneontology |
| http://linkedlifedata.com/r... | skos:prefLabel | apoptotic process | lld:geneontology |
| http://linkedlifedata.com/r... | skos:altLabel | apoptotic cell death | lld:geneontology |
| http://linkedlifedata.com/r... | skos:altLabel | apoptotic programmed cell death | lld:geneontology |
| http://linkedlifedata.com/r... | skos:altLabel | programmed cell death by apoptosis | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_100045 "Apoptosis, Drosophila melanogaster" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_100962 "Apoptosis, Mus musculus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_101249 "NRIF signals cell death from the nucleus, Danio rerio" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_104187 "NRAGE signals death through JNK, Taeniopygia guttata" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_105149 "NADE modulates death signalling, Rattus norvegicus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_106405 "NRAGE signals death through JNK, Xenopus tropicalis" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_106672 "NADE modulates death signalling, Sus scrofa" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_107264 "NRIF signals cell death from the nucleus, Xenopus tropicalis" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_108651 "NRAGE signals death through JNK, Mus musculus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_109165 "NRAGE signals death through JNK, Arabidopsis thaliana" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_110081 "NRAGE signals death through JNK, Schizosaccharomyces pombe" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_111964 "NRAGE signals death through JNK, Dictyostelium discoideum" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_13526 "NADE modulates death signalling, Homo sapiens" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_13638 "NRAGE signals death through JNK, Homo sapiens" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_13643 "NRIF signals cell death from the nucleus, Homo sapiens" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_28087 "Apoptosis, Saccharomyces cerevisiae" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_28795 "Apoptosis, Oryza sativa" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_28816 "Apoptosis, Danio rerio" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_30266 "Apoptosis, Arabidopsis thaliana" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_30361 "Apoptosis, Canis familiaris" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_30371 "NRAGE signals death through JNK, Saccharomyces cerevisiae" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_30548 "NRAGE signals death through JNK, Caenorhabditis elegans" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_30763 "NRAGE signals death through JNK, Oryza sativa" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_31349 "NRAGE signals death through JNK, Canis familiaris" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_34139 "NRAGE signals death through JNK, Gallus gallus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_578 "Apoptosis, Homo sapiens" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_77132 "NRAGE signals death through JNK, Drosophila melanogaster" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_77313 "NADE modulates death signalling, Bos taurus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_77415 "NRIF signals cell death from the nucleus, Canis familiaris" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_78287 "Apoptosis, Gallus gallus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_78802 "NADE modulates death signalling, Canis familiaris" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_79809 "Apoptosis, Schizosaccharomyces pombe" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_82724 "Apoptosis, Taeniopygia guttata" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_83328 "Apoptosis, Sus scrofa" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_85877 "NRAGE signals death through JNK, Rattus norvegicus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_86749 "Apoptosis, Rattus norvegicus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_86873 "NRIF signals cell death from the nucleus, Gallus gallus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_87570 "NRIF signals cell death from the nucleus, Rattus norvegicus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_88740 "NRIF signals cell death from the nucleus, Sus scrofa" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_88784 "NRIF signals cell death from the nucleus, Mus musculus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_89196 "Apoptosis, Dictyostelium discoideum" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_90267 "NRIF signals cell death from the nucleus, Taeniopygia guttata" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_91011 "Apoptosis, Caenorhabditis elegans" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_91243 "NADE modulates death signalling, Mus musculus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_93937 "Apoptosis, Bos taurus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_94099 "NRAGE signals death through JNK, Danio rerio" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_95069 "Apoptosis, Xenopus tropicalis" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_95675 "Apoptosis, Plasmodium falciparum" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_97627 "NRIF signals cell death from the nucleus, Bos taurus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_99784 "NRAGE signals death through JNK, Bos taurus" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Reactome:REACT_99799 "NRAGE signals death through JNK, Sus scrofa" | lld:geneontology |
| http://linkedlifedata.com/r... | skos:notation | Wikipedia:Apoptosis | lld:geneontology |
| http://linkedlifedata.com/r... | skos:broader | http://linkedlifedata.com/r... | lld:geneontology |
| http://linkedlifedata.com/r... | skos:relatedSynonym | signaling (initiator) caspase activity | lld:geneontology |
| http://linkedlifedata.com/r... | skos:narrowSynonym | apoptosis | lld:geneontology |
| http://linkedlifedata.com/r... | skos:narrowSynonym | apoptotic program | lld:geneontology |
| http://linkedlifedata.com/r... | skos:narrowSynonym | type I programmed cell death | lld:geneontology |
| http://linkedlifedata.com/r... | skos:broadSynonym | cell suicide | lld:geneontology |
| http://linkedlifedata.com/r... | skos:broadSynonym | cellular suicide | lld:geneontology |
| uniprot-protein:P20333 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P01584 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P21802 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P22607 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P29274 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:O95470 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q9H6Z9 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P54577 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q9NS18 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P28331 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q03181 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P05771 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P00519 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q13564 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P63000 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P35348 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P30536 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q99460 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q13200 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P20618 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P28074 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P49721 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P04049 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P61073 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P05107 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P12236 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P10997 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P19838 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P29317 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P49747 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P21796 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P01138 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P80188 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q14289 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P06493 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P47929 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P19438 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P53355 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P37173 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:O15169 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q01064 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q9BUP3 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P26662 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P68403 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P20171 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P26663 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P05884 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P12488 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P00639 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P81382 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q6STF1 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q90W54 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P26660 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P03519 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q05652 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q02248 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P80204 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P35961 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q62048 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P63244 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q13501 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P61289 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q13323 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q13352 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q96CJ1 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q96J02 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q9UNL4 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q14728 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q9UDX5 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q9H2J4 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q8WU39 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P40306 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q92835 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:O94768 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q9UMX0 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q969W1 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:O35465 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P58283 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q8VCQ6 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q5D1E7 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q5VST9 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P61077 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q14318 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q658P3 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q9TT15 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:A2VEA7 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:A0PJW8 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q9D757 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:O75618 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P62951 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q91UZ4 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:P53347 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q28IA3 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q498F8 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q9JHE3 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q9Z0F3 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q9D2C7 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q4V7N8 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:A4IHR0 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
| uniprot-protein:Q8C052 | relontology:participateInBi... | http://linkedlifedata.com/r... | lld:causality |
