F3257B859336A80D576543F4C9E90DDE7DB0D2DC7C25FB81A85B188BD28D934BCB4EB82BA005D0E7ED2EED5CB648A402

The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity).

Source:http://purl.uniprot.org/SHA-384/F3257B859336A80D576543F4C9E90DDE7DB0D2DC7C25FB81A85B188BD28D934BCB4EB82BA005D0E7ED2EED5CB648A402

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