Dually phosphorylated on Thr-186 and Tyr-188, which activates the enzyme.
Source:http://purl.uniprot.org/SHA-384/C69F416641B7FBC0988EB36289EBDB49F88198738803F6C5ED525272D8013A06FF15717E0F89CD13B73E40BFF996D388
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