In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm (By similarity).
Source:http://purl.uniprot.org/SHA-384/A5D9E61B97A0F24CF98893D5E0EB7B8BEE6AD6E0923B7BCB6CFDFE519B8AAB3189B5BB37F9D27148FBADBA2F2748CC29
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