The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway) (By similarity).
Source:http://purl.uniprot.org/SHA-384/7B9D1B741FFDED6E927F7EEF892842DEB3A6D1F66EBD1B2C803FCC4FB813A0971568550635647331E3AA4B3001010C5C
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