4DE8D97EC45BEF9907A930913E05D343D75DB02BEB0A8E0D87D1E7C2951CC97AC72C35A450CA78A5FF59266F19A5ADB2

Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols. Binding of f 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses. Promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity). Signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha. Signals constitutively also via MAPK1/3 (ERK1/2) (By similarity).

Source:http://purl.uniprot.org/SHA-384/4DE8D97EC45BEF9907A930913E05D343D75DB02BEB0A8E0D87D1E7C2951CC97AC72C35A450CA78A5FF59266F19A5ADB2

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