deoxyhypusine synthase activity

Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+.

Source:http://purl.uniprot.org/go/0034038

Download in:

Named Graph Language Inference

Statements in which the resource exists as a object.
Subject	Predicate
http://purl.uniprot.org/go/0016765	skos:narrower
uniprot-protein:P49366, uniprot-protein:Q6EWQ6, uniprot-protein:Q811L9, uniprot-protein:Q6AY53, uniprot-protein:O28088, uniprot-protein:Q8TS38, uniprot-protein:Q8PV89, uniprot-protein:O27984, uniprot-protein:Q8TLM3, uniprot-protein:Q8Q051, uniprot-protein:Q9YE72, uniprot-protein:Q9FI94, uniprot-protein:Q75EW4, uniprot-protein:Q9XXJ0, uniprot-protein:Q6FRN2, uniprot-protein:Q6BJH5, uniprot-protein:Q54MQ7, uniprot-protein:Q9VSF4, uniprot-protein:Q8SQN2, uniprot-protein:B0R5L2, uniprot-protein:Q9HPX2, uniprot-protein:A8AA61, uniprot-protein:Q6CNG7, uniprot-protein:Q58224, uniprot-protein:Q8TXD7, uniprot-protein:A4YHK6, uniprot-protein:O26230, uniprot-protein:A6URC0, uniprot-protein:Q3TXU5, uniprot-protein:P49365, uniprot-protein:Q6KZL5, uniprot-protein:Q9V0N5, uniprot-protein:Q8ZT09, uniprot-protein:A3MVC9, uniprot-protein:Q8U407, uniprot-protein:O50105, uniprot-protein:Q5JEY0, uniprot-protein:O94337, uniprot-protein:Q9AXR0, uniprot-protein:Q4J978, uniprot-protein:C3N5B4, uniprot-protein:C4KGY0, uniprot-protein:C3MPN8, uniprot-protein:C3MYN2, uniprot-protein:C3NHT5, uniprot-protein:C3NDW8, uniprot-protein:Q97ZF1, uniprot-protein:Q971T3, uniprot-protein:Q9HL74, uniprot-protein:C5A5L0, uniprot-protein:B6YVB1, uniprot-protein:Q97BN6, uniprot-protein:Q6CG56, uniprot-protein:P38791, uniprot-protein:G0EC86, uniprot-protein:G4RP83, uniprot-protein:G0H1E4, uniprot-protein:G0HXU3, uniprot-protein:G2MLT3, uniprot-protein:F8D8L9, uniprot-protein:B5IFC0, uniprot-protein:Q2FT95, uniprot-protein:Q2FTM2, uniprot-protein:D3RX15, uniprot-protein:B1YDD5, uniprot-protein:D3RY86, uniprot-protein:E3GX03, uniprot-protein:A4G052, uniprot-protein:F8AIU4, uniprot-protein:A3DP94, uniprot-protein:D9PZY8, uniprot-protein:Q0W123, uniprot-protein:Q0W776, uniprot-protein:Q6M0Y1, uniprot-protein:D7E894, uniprot-protein:A8MDF2, uniprot-protein:E4NUL2, uniprot-protein:A4WMA0, uniprot-protein:Q3INC3, uniprot-protein:F0TB50, uniprot-protein:D7D8T9, uniprot-protein:A2SPS5, uniprot-protein:A5UNP2, uniprot-protein:D5E895, uniprot-protein:B1L479, uniprot-protein:Q46GE1, uniprot-protein:D2RGK2, uniprot-protein:D5VR75, uniprot-protein:F4B4S1, uniprot-protein:Q46AX0, uniprot-protein:C9REE8, uniprot-protein:D5U1D9, uniprot-protein:F4HM67, uniprot-protein:A0B8F7, uniprot-protein:F4G084, uniprot-protein:A0B8D8, uniprot-protein:Q18GE0, uniprot-protein:A6UX27, uniprot-protein:A1RX92	uniprot:classifiedWith

More...