Engagement of killer inhibitory receptors (KIR) disrupts the interaction of PLCG1 with LAT and blocks target cell-induced activation of PLC, maybe by inducing the dephosphorylation of LAT (By similarity).
Source:http://purl.uniprot.org/SHA-384/1B1B5FD025ABB8D8CB409A9FE93B205A438D4CA6EC6CD1CA358D8239150672A5BD91ECB1B7563832D2DB491ECC646253
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