http://purl.uniprot.org/go/... | rdf:type | uniprot:Concept | lld:uniprot |
http://purl.uniprot.org/go/... | rdfs:comment | An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of heart contraction. Binding of adrenalin or noradrenalin to a beta-adrenergic receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gs protein. Gs activates adenylate cyclase to increase intracellular cyclic-AMP (cAMP) levels. cAMP binds directly to F-channels to allow an inward flow of sodium (known as funny current, or If current). The funny current is responsible for membrane depolarization and an increase in heart rate. | lld:uniprot |
http://purl.uniprot.org/go/... | rdfs:subClassOf | http://purl.uniprot.org/go/... | lld:uniprot |
http://purl.uniprot.org/go/... | rdfs:subClassOf | http://purl.uniprot.org/go/... | lld:uniprot |
http://purl.uniprot.org/go/... | rdfs:subClassOf | http://purl.uniprot.org/go/... | lld:uniprot |
http://purl.uniprot.org/go/... | rdfs:subClassOf | http://purl.uniprot.org/go/... | lld:uniprot |
http://purl.uniprot.org/go/... | rdfs:label | adrenergic receptor signaling pathway involved in positive regulation of heart rate | lld:uniprot |
http://purl.uniprot.org/go/... | rdfs:label | activation of funny current by beta-adrenergic receptor signaling pathway | lld:uniprot |
http://purl.uniprot.org/go/... | rdfs:label | adenylate cyclase-activating cardiac adrenergic receptor signaling pathway | lld:uniprot |
http://purl.uniprot.org/go/... | rdfs:label | adrenergic receptor signalling pathway involved in positive regulation of heart rate | lld:uniprot |
http://purl.uniprot.org/go/... | rdfs:label | beta adrenergic receptor signaling pathway involved in positive regulation of heart rate | lld:uniprot |
http://purl.uniprot.org/go/... | rdfs:label | Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate | lld:uniprot |
http://purl.uniprot.org/go/... | rdfs:label | If activation by beta-adrenergic receptor signaling pathway | lld:uniprot |
http://purl.uniprot.org/go/... | skos:exactMatch | http://www.geneontology.org... | lld:uniprot |
http://purl.uniprot.org/go/... | skos:narrower | http://purl.uniprot.org/go/... | lld:uniprot |
http://purl.uniprot.org/go/... | skos:narrower | http://purl.uniprot.org/go/... | lld:uniprot |
http://purl.uniprot.org/go/... | skos:narrower | http://purl.uniprot.org/go/... | lld:uniprot |
http://purl.uniprot.org/go/... | skos:narrower | http://purl.uniprot.org/go/... | lld:uniprot |