| http://purl.uniprot.org/enz... | rdf:type | uniprot:Enzyme | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | Belongs to peptidase family M9. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | Six species of metalloendopeptidase acting on native collagen can be isolated from the medium of Clostridium histolyticum. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | Class I has forms alpha (68 kDa), beta (115 kDa) and gamma (79 kDa); class II has delta (100 kDa), epsilon (110 kDa) and zeta (125 kDa). | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | The two classes are immunologically crossreactive, but have significantly different sequences, and different specificities such that their actions on collagen are complementary. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | The enzymes also act as peptidyl-tripeptidases. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | Variants of the enzyme have been purified from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio, Vibrio B-30 (ATCC 21250) and V.alginolyticus (previously Achromobacter iophagus). | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | Also known from Streptomyces sp. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:subClassOf | http://purl.uniprot.org/enz... | lld:uniprot |
| http://purl.uniprot.org/enz... | skos:broaderTransitive | http://purl.uniprot.org/enz... | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Microbial collagenase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Clostridiopeptidase A | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Clostridium histolyticum collagenase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Collagenase A | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Collagenase I | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:replaces | http://purl.uniprot.org/enz... | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:replaces | http://purl.uniprot.org/enz... | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:replaces | http://purl.uniprot.org/enz... | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:activity | Digestion of native collagen in the triple helical region at Xaa-|-Gly bonds. With synthetic peptides, a preference is shown for Gly at P3 and P1'; Pro and Ala at P2 and P2'; and hydroxyproline, Ala or Arg at P3'. | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:cofactor | Zinc | lld:uniprot |
| http://purl.uniprot.org/enz... | skos:narrowerTransitive | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:P43153 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q9KRJ0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q56696 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q8D4Y9 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B6KCU5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q4QHH0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E8VWS0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E8VXH7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F4A9Z1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A5I290 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q81YS7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A7K0C6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A7K2C6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B7JPE4 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A9VUP8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A9VTN8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A3D8Z3 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D2AQQ5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A9VNP0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A9VK61 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B1HXW1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A7GL33 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q1CZ37 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C3NZD5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C0ZHZ8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C0ZG57 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C3NQ32 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E1SV87 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D3Q996 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q73DU5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A7GDU8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q8D4D6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C7PYZ6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q6HNQ7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q6HFR8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q0SWK1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C1FN87 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C6S8B2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q39NP4 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B8CS56 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B8CU71 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A4FE85 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B1KDE3 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B1KQW1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B1KCW8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A3NIP2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A0PYC6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D8H6F4 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A3NI16 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D8H0R2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B1L1W8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B1ILP0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B2TJU5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A1S5R8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C1DC29 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A1S4H8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A3P4B7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B8E8R6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A3P3M6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A0RGT1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A0R9J4 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A6WJ02 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A3QGL1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A3QJF0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A3QDK4 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E4N0U6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E4N9N1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E4NAU0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q0TUR0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B2UZP8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B0TMN1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B0TLD4 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E8SDD1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B0TPF7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A7FUC7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q7NWM8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q7P1E7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B7H8B8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q7NWI8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A8FP79 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A8FYI1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B7HV61 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C3LGK8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q81I63 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q81AY5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q81AN3 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q81DA6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q81BX9 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q81A31 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q817Z3 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q81BX8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q81BJ6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q482Q5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q485R5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q637U3 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q63G89 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q4V1V2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B7IWT0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A9L0A6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
