| http://purl.uniprot.org/enz... | rdf:type | uniprot:Enzyme | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | In Saccharomyces cerevisiae, the last two steps are carried out by a single bifunctional enzyme, Met8p. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | This enzyme catalyzes two sequential methylation reactions, the first forming precorrin-1 and the second leading to the formation of precorrin-2. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | It is the first of three steps leading to the formation of siroheme from uroporphyrinogen III. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | The second step involves an NAD(+)-dependent dehydrogenation to form sirohydrochlorin from precorrin-2 (EC 1.3.1.76) and the third step involves the chelation of Fe(2+) to sirohydrochlorin to form siroheme (EC 4.99.1.4). | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | In some bacteria, steps 1-3 are catalyzed by a single multifunctional protein called CysG, whereas in Bacillus megaterium, three separate enzymes carry out each of the steps, with SirA being responsible for the above reaction. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:comment | Also involved in the biosynthesis of cobalamin. | lld:uniprot |
| http://purl.uniprot.org/enz... | rdfs:subClassOf | http://purl.uniprot.org/enz... | lld:uniprot |
| http://purl.uniprot.org/enz... | skos:broaderTransitive | http://purl.uniprot.org/enz... | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Urogen III methylase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | SUMT | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Uroporphyrinogen III methylase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Uroporphyrinogen-III C-methyltransferase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Uroporphyrin-III C-methyltransferase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Uroporphyrinogen-III methyltransferase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Uroporphyrinogen-III methylase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Adenosylmethionine-uroporphyrinogen III methyltransferase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:name | Uroporphyrinogen methyltransferase | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:activity | (1) S-adenosyl-L-methionine + uroporphyrinogen III = S-adenosyl-L-homocysteine + precorrin-1. | lld:uniprot |
| http://purl.uniprot.org/enz... | uniprot:activity | (2) S-adenosyl-L-methionine + precorrin-1 = S-adenosyl-L-homocysteine + precorrin-2. | lld:uniprot |
| http://purl.uniprot.org/enz... | skos:narrowerTransitive | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:P21631 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:P09127 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:P42437 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q51701 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:O34744 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:O19889 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q58375 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q9I2W4 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:O74468 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:P42451 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q55749 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:P36150 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G4RKT9 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G4RNE0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G4RJU1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G0H0B5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G0HSE1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F8D2Z6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q2FTK8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B1YBC1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E3GX90 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A4FY15 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B0R7M3 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D9Q2R9 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q6LYM4 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q0W5T1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E4NS70 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q3ISY0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q4J6U5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q4JAA3 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F0TBZ4 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E1RG47 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A5UNH7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D5EA84 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q46BL0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A0B883 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q18ES2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q8Q031 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A4YED1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A2BL25 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F8AJQ0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F6BBI7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A3CU67 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D3E4D0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q5UY51 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C3NKN4 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q12WZ3 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C3MLE1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C3MKB2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q6KZ32 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D4GYS2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D9PVG5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q974U8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F6D4P8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q9YFL2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F7XNF0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q97W12 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F2KQA0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F2KRS9 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C3NAY2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q97UT5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q4WWP5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B9WAV1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B9WAX8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A3LUM7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A3LZI7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:A2QMI3 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:Q42606 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B9THR9 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:B9RHK7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C9LXX9 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G0EV17 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G0EUD5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F8GTF6 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:O68101 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F4CZR9 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E8VUK1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E8VUN0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G4NS88 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F6F0G7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F6EVH5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F9YI44 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:E3Y8W5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D7BIW8 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G2SIX2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G0BHQ1 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G0BLR5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G2Z084 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:G2KUU5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F8CSB0 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F8CSL2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:C4KSJ7 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F6IKB4 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F6IK82 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D8NQH5 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D8P0A2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D8P042 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:D8NR30 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
| uniprot-protein:F4A5D3 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
