http://purl.uniprot.org/enz... | rdf:type | uniprot:Enzyme | lld:uniprot |
http://purl.uniprot.org/enz... | rdfs:comment | The bifunctional enzyme from Aspergillus nidulans uses different heme domains to catalyze two separate reactions. | lld:uniprot |
http://purl.uniprot.org/enz... | rdfs:comment | Linoleic acid is oxidized within the N-terminal heme peroxidase domain to (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate, which is subsequently isomerized by the C-terminal P450 heme thiolate domain to (5S,8R,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate (cf. EC 5.4.4.5). | lld:uniprot |
http://purl.uniprot.org/enz... | rdfs:comment | The bifunctional enzyme from Gaeumannomyces graminis also catalyzes the oxidation of linoleic acid to (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate, but its second domain isomerizes it to (7S,8S,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate (cf. EC 5.4.4.6). | lld:uniprot |
http://purl.uniprot.org/enz... | rdfs:subClassOf | http://purl.uniprot.org/enz... | lld:uniprot |
http://purl.uniprot.org/enz... | skos:broaderTransitive | http://purl.uniprot.org/enz... | lld:uniprot |
http://purl.uniprot.org/enz... | uniprot:name | Linoleate 8R-lipoxygenase | lld:uniprot |
http://purl.uniprot.org/enz... | uniprot:name | 5,8-linoleate diol synthase (bifunctional enzyme) | lld:uniprot |
http://purl.uniprot.org/enz... | uniprot:name | 7,8-linoleate diol synthase (bifunctional enzyme) | lld:uniprot |
http://purl.uniprot.org/enz... | uniprot:replaces | http://purl.uniprot.org/enz... | lld:uniprot |
http://purl.uniprot.org/enz... | uniprot:activity | Linoleate + O(2) = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate. | lld:uniprot |
http://purl.uniprot.org/enz... | uniprot:cofactor | Heme | lld:uniprot |
http://purl.uniprot.org/enz... | skos:narrowerTransitive | http://purl.uniprot.org/enz... | lld:uniprot |
uniprot-protein:Q9UUS2 | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
http://purl.uniprot.org/SHA... | uniprot:enzyme | http://purl.uniprot.org/enz... | lld:uniprot |
http://purl.uniprot.org/enz... | uniprot:replacedBy | http://purl.uniprot.org/enz... | lld:uniprot |