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http://purl.uniprot.org/cit... | rdfs:comment | The complete genomes of three new Type 1 strains of JC virus (JCV) from urine have been analysed. These were subtype 1A, subtype 1B and Type 4 as assigned from a short typing fragment in the VP1 gene. They differ from Mad1 (subtype 1A) by less than 1.0% of the DNA sequence. Based on its complete genome, the JCV Type 4 strain falls into a Type 1 subgroup. Type 4, with several Type 3-like sites in the short typing fragment, is a possible recombinant strain. The consensus of Type 1 DNA sequences is distinguished within the coding region from both Type 2 (strain GS/B) and five Type 3 (African and African American) strains at 64 sites. Most mutations are silent, but at 21 positions amino acid changes occur. Our findings define the subtypes of JCV Type 1 and support the validity of genotyping within the short VP1 fragment. | lld:uniprot |
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http://purl.uniprot.org/cit... | uniprot:name | J. Gen. Virol. | lld:uniprot |
http://purl.uniprot.org/cit... | uniprot:author | Stoner G.L. | lld:uniprot |
http://purl.uniprot.org/cit... | uniprot:author | Agostini H.T. | lld:uniprot |
http://purl.uniprot.org/cit... | uniprot:author | Ryschkewitsch C.F. | lld:uniprot |
http://purl.uniprot.org/cit... | uniprot:date | 1998 | lld:uniprot |
http://purl.uniprot.org/cit... | uniprot:pages | 801-805 | lld:uniprot |
http://purl.uniprot.org/cit... | uniprot:title | JC virus Type 1 has multiple subtypes: three new complete genomes. | lld:uniprot |
http://purl.uniprot.org/cit... | uniprot:volume | 79 | lld:uniprot |
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