Acetyl-CoA + 3-methyl-2-oxobutanoate + H(2)O = (2S)-2-isopropylmalate + CoA.
Source:http://purl.uniprot.org/SHA-384/78DCF692DECB27E00B96F4F77F2B1B865F4D238378370A844FB86AC2C72E14485A1F96D0C1AB721F3FEA46B78B5A8A0F
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