Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7 (By similarity).
Subject | Predicate | Object | Context |
---|---|---|---|
http://purl.uniprot.org/SHA... | rdf:type | uniprot:Function_Annotation | lld:uniprot |
http://purl.uniprot.org/SHA... | rdfs:comment | Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7 (By similarity). | lld:uniprot |
uniprot-protein:Q69ZB3 | uniprot:annotation | http://purl.uniprot.org/SHA... | lld:uniprot |