Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues (By similarity).
| Subject | Predicate | Object | Context |
|---|---|---|---|
| http://purl.uniprot.org/SHA... | rdf:type | uniprot:Function_Annotation | lld:uniprot |
| http://purl.uniprot.org/SHA... | rdfs:comment | Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues (By similarity). | lld:uniprot |
| uniprot-protein:Q7LGA3 | uniprot:annotation | http://purl.uniprot.org/SHA... | lld:uniprot |
| uniprot-protein:Q5R621 | uniprot:annotation | http://purl.uniprot.org/SHA... | lld:uniprot |
| uniprot-protein:O08889 | uniprot:annotation | http://purl.uniprot.org/SHA... | lld:uniprot |