| family:PF10425.4 | rdf:type | pfam:Family | lld:pfam |
| family:PF10425.4 | family:comment | This is the C-terminal half of a bacterial fibrinogen-bindingadhesin SdrG. SdrG is a Gram-positive cell-wall-anchored adhesin that allows attachment of the bacterium to host tissues via specific binding to the beta-chain of human fibrinogen (Fg). SdrG binds to its ligand with a dynamic "dock, lock, and latch" mechanism which represents a general mode of ligand-binding for structurally related cell wall-anchored proteins in most Gram-positive bacteria. The C-terminal part of SdrG(276-596) is integral to the folding of the immunoglobulin-like whole to create the docking grooves necessary for Fg binding. The domain is associated with families of Cna_B, Pfam:PF05738 [1]. | lld:pfam |
| family:PF10425.4 | family:id | SdrG_C_C | lld:pfam |
| family:PF10425.4 | family:description | C-terminus of bacterial fibrinogen-binding adhesin | lld:pfam |
| family:PF10425.4 | family:authorList | Finn RD, Coggill PC | lld:pfam |
| family:PF10425.4 | family:familyType | Domain | lld:pfam |
| family:PF10425.4 | family:dbReference | http://linkedlifedata.com/r... | lld:pfam |
| family:PF10425.4 | family:pubmed | pubmed-article:14567919 | lld:pfam |
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| family:PF10425.4 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF10425.4 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
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| family:PF10425.4 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF10425.4 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
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| family:PF10425.4 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
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