| family:PF07915.8 | rdf:type | pfam:Family | lld:pfam |
| family:PF07915.8 | family:comment | The sequences found in this family are similar to a region foundin the beta-subunit of glucosidase II (Swiss:P14314), which is also known as protein kinase C substrate 80K-H (PRKCSH). The enzyme catalyses the sequential removal of two alpha-1,3-linked glucose residues in the second step of N-linked oligosaccharide processing [1]. The beta subunit is required for the solubility and stability of the heterodimeric enzyme, and is involved in retaining the enzyme within the endoplasmic reticulum [1]. Mutations in the gene coding for PRKCSH have been found to be involved in the development of autosomal dominant polycystic liver disease (ADPLD), but the precise role the protein has in the pathogenesis of this disease is unknown [2]. This family also includes an ER sensor for misfolded glycoproteins and is therefore likely to be a generic sugar binding domain. | lld:pfam |
| family:PF07915.8 | family:id | PRKCSH | lld:pfam |
| family:PF07915.8 | family:description | Glucosidase II beta subunit-like protein | lld:pfam |
| family:PF07915.8 | family:authorList | Fenech M | lld:pfam |
| family:PF07915.8 | family:familyType | Family | lld:pfam |
| family:PF07915.8 | family:dbReference | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:pubmed | pubmed-article:12529853 | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF07915.8 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
