| family:PF02344.10 | rdf:type | pfam:Family | lld:pfam |
| family:PF02344.10 | family:comment | This family consists of the leucine zipper dimerisation domainfound in both cellular c-Myc proto-oncogenes and viral v-Myc oncogenes. Dimerisation via the leucine zipper motif with other basic helix-loop-helix-leucine zipper (b/HLH/lz) proteins such as Max Swiss:P25912 is required for efficient DNA binding. The Myc-Max dimer is a transactivating complex activating expression of growth related genes promoting cell proliferation. The dimerisation is facilitated via interdigitating leucine residues every 7th position of the alpha helix. Like charge repulsion of adjacent residues in this region perturbs the formation of homodimers with heterodimers being promoted by opposing charge attractions. | lld:pfam |
| family:PF02344.10 | family:id | Myc-LZ | lld:pfam |
| family:PF02344.10 | family:description | Myc leucine zipper domain | lld:pfam |
| family:PF02344.10 | family:authorList | Bashton M, Bateman A | lld:pfam |
| family:PF02344.10 | family:familyType | Family | lld:pfam |
| family:PF02344.10 | family:dbReference | http://linkedlifedata.com/r... | lld:pfam |
| family:PF02344.10 | family:pubmed | pubmed-article:9680483 | lld:pfam |
| family:PF02344.10 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| family:PF02344.10 | family:protein | http://linkedlifedata.com/r... | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | family:PF02344.10 | lld:pfam |
