http://linkedlifedata.com/r... | rdf:type | entrezgene:HIVInteraction | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:9079628 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:12419264 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:14550573 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15356131 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:interactant | entrez-gene:5699 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:geneRifText | HIV-1 Tat inhibits the peptidase activity of the 20 S proteasome and interferes with the formation of the 20 S proteasome-11 S regulator complex | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:geneRifText | HIV-1 Tat slightly enhances the activity of the purified 26 S proteasome | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:geneRifText | Amino acids Lys51, Arg52, and Asp67 of HIV-1 Tat represent the proteasome binding site of Tat, and Tat amino acids 37-72 are necessary for proteasomal interaction and suppression of 11 S regulator-mediated antigen presentation | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:geneRifText | HIV-1 Tat binds to the alpha2, alpha4, alpha6, alpha7, beta1, beta2, beta3, beta5, beta6, beta7, LMP7/beta5i, and MECL1/beta2i subunits of the proteasome 20 S core structure and can inhibit cellular proteasome function | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:geneRifText | HIV-1 Tat upregulates LMP7 and MECL1 catalytic subunits of the proteasome resulting in a more efficient generation and presentation of subdominant MHC-I-binding CTL epitopes of heterologous Ags | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:keyphrase | inhibits | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:keyphrase | interacts with | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:keyphrase | upregulates | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:keyphrase | binds | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:keyphrase | enhances | lld:entrezgene |
entrez-gene:155871 | entrezgene:hivInteraction | http://linkedlifedata.com/r... | lld:entrezgene |