http://linkedlifedata.com/r... | rdf:type | entrezgene:HIVInteraction | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:20012529 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:20347598 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15142382 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:12573582 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15302882 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:19581932 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:interactant | entrez-gene:1026 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:geneRifText | Activation of p21/Waf1/Cip1 by HIV-1 Vpr appears to be dependent upon p53 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:geneRifText | HIV-1 Vpr activates the expression and transcription of the cyclin-dependent kinase inhibitor p21/Waf1/Cip1, an inhibitor of the G1 and G2/M phase transitions in T lymphoid and myeloid cells | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:geneRifText | HIV-1 Vpr activates promoter activity of p21/Cip1/Waf1 through the GC-rich region located between nucleotides -84 and -74 in a manner that requires cooperativity of Sp1, which binds to the DNA sequence spanning -84 to -74 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:geneRifText | Results from GST pull-down assays show the association of Vpr with p53 in extracts containing Sp1, suggesting the physical interaction of Vpr with Sp1 and p53 could modulate transcriptional activity of p21 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:geneRifText | COUP-TF-interacting protein 2 (CTIP2) abolishes Vpr-mediated stimulation of p21 by cooperating with SUV39H1 and HDAC1/HDAC2 to silence the p21 gene transcription | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:keyphrase | interacts with | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:keyphrase | upregulates | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:keyphrase | activates | lld:entrezgene |
entrez-gene:155807 | entrezgene:hivInteraction | http://linkedlifedata.com/r... | lld:entrezgene |