Source:http://linkedlifedata.com/resource/#_5139563050390013
| Subject | Predicate | Object | Context |
|---|---|---|---|
| http://linkedlifedata.com/r... | rdf:type | rdf:Statement | lld:uniprot |
| http://linkedlifedata.com/r... | uniprot:attribution | http://linkedlifedata.com/r... | lld:uniprot |
| http://linkedlifedata.com/r... | rdf:subject | http://purl.uniprot.org/SHA... | lld:uniprot |
| http://linkedlifedata.com/r... | rdf:predicate | rdfs:comment | lld:uniprot |
| http://linkedlifedata.com/r... | rdf:object | Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity). | lld:uniprot |