Statements in which the resource exists.
SubjectPredicateObjectContext
http://linkedlifedata.com/r...rdf:typerdf:Statementlld:uniprot
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http://linkedlifedata.com/r...rdf:subjecthttp://purl.uniprot.org/SHA...lld:uniprot
http://linkedlifedata.com/r...rdf:predicaterdfs:commentlld:uniprot
http://linkedlifedata.com/r...rdf:objectSerine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Recruited to DNA lesions in order to initiate the DNA repair by homologous recombination. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, also involved in the regulation of DNA damage response mechanism. Required for cell growth and meiotic recombination (By similarity).lld:uniprot