Source:http://linkedlifedata.com/resource/#_5138535345370014
Subject | Predicate | Object | Context |
---|---|---|---|
http://linkedlifedata.com/r... | rdf:type | rdf:Statement | lld:uniprot |
http://linkedlifedata.com/r... | uniprot:attribution | http://linkedlifedata.com/r... | lld:uniprot |
http://linkedlifedata.com/r... | rdf:subject | http://purl.uniprot.org/SHA... | lld:uniprot |
http://linkedlifedata.com/r... | rdf:predicate | rdfs:comment | lld:uniprot |
http://linkedlifedata.com/r... | rdf:object | Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Recruited to DNA lesions in order to initiate the DNA repair by homologous recombination. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, also involved in the regulation of DNA damage response mechanism. Required for cell growth and meiotic recombination (By similarity). | lld:uniprot |