Source:http://linkedlifedata.com/resource/#_5037393438330071
| Subject | Predicate | Object | Context |
|---|---|---|---|
| http://linkedlifedata.com/r... | rdf:type | rdf:Statement | lld:uniprot |
| http://linkedlifedata.com/r... | uniprot:attribution | http://linkedlifedata.com/r... | lld:uniprot |
| http://linkedlifedata.com/r... | rdf:subject | http://purl.uniprot.org/SHA... | lld:uniprot |
| http://linkedlifedata.com/r... | rdf:predicate | rdfs:comment | lld:uniprot |
| http://linkedlifedata.com/r... | rdf:object | Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of antigenic peptides. | lld:uniprot |