Linked Life Data

Q13905

Source:http://identifiers.org/uniprot/Q13905

Statements in which the resource exists.
SubjectPredicateObjectContext
http://identifiers.org/unip...rdf:typebiopax3:ProteinReferencelld:biopax3
http://identifiers.org/unip...biopax3:commentSEQUENCE 1077 AA; 120548 MW; E700631A0EE76CA1 CRC64;lld:biopax3
http://identifiers.org/unip...biopax3:commentFUNCTION: Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. SUBUNIT: Interacts with CRK via its SH3-binding sites. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=Long; IsoId=Q13905-1; Sequence=Displayed; Name=Short; IsoId=Q13905-2; Sequence=VSP_001822; Name=3; IsoId=Q13905-3; Sequence=VSP_042052; Note=No experimental confirmation available; TISSUE SPECIFICITY: Ubiquitously expressed in adult and fetus. Expression is high in adult skeletal muscle and placenta and in fetal brain and heart. Low levels of expression in adult and fetal liver. PTM: Phosphorylation at Tyr-504 enhances activity as Rap guanine nucleotide exchange factor. SIMILARITY: Contains 1 N-terminal Ras-GEF domain. SIMILARITY: Contains 1 Ras-GEF domain. GENE SYNONYMS:RAPGEF1 GRF2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biopax3
http://identifiers.org/unip...biopax3:xrefurn:biopax:UnificationXref:...lld:biopax3
http://identifiers.org/unip...biopax3:xrefurn:biopax:RelationshipXref...lld:biopax3
http://identifiers.org/unip...biopax3:xrefurn:biopax:UnificationXref:...lld:biopax3
http://identifiers.org/unip...biopax3:xrefurn:biopax:RelationshipXref...lld:biopax3
http://identifiers.org/unip...biopax3:xrefurn:biopax:UnificationXref:...lld:biopax3
http://identifiers.org/unip...biopax3:xrefurn:biopax:RelationshipXref...lld:biopax3
http://identifiers.org/unip...biopax3:xrefurn:biopax:RelationshipXref...lld:biopax3
http://identifiers.org/unip...biopax3:displayNameRPGF1_HUMANlld:biopax3
http://identifiers.org/unip...biopax3:nameRAPGEF1lld:biopax3
http://identifiers.org/unip...biopax3:nameCRK SH3-binding GNRPlld:biopax3
http://identifiers.org/unip...biopax3:nameProtein C3Glld:biopax3
http://identifiers.org/unip...biopax3:nameGuanine nucleotide-releasing factor 2lld:biopax3
http://identifiers.org/unip...biopax3:entityFeatureurn:biopax:ModificationFeat...lld:biopax3
http://identifiers.org/unip...biopax3:entityFeatureurn:biopax:ModificationFeat...lld:biopax3
http://identifiers.org/unip...biopax3:entityFeatureurn:biopax:ModificationFeat...lld:biopax3
http://identifiers.org/unip...biopax3:entityFeatureurn:biopax:ModificationFeat...lld:biopax3
http://identifiers.org/unip...biopax3:organismhttp://identifiers.org/taxo...lld:biopax3
http://identifiers.org/unip...biopax3:sequenceMDTDSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVKIPEKPVNKEATDRFLPEGYPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSSPASKPDGPAELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPPPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQTAWNLSPLPESLGESGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRRSAASQTADGSGCRVSYERHPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPVEFVGDFTAPESTGDPEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQKNKLLMEVYGFSDSFSGVDSVQELAPPPALPPKQRQLEPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKSPDALESAQSEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVELTEEILKLLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRWQQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKTlld:biopax3
http://identifiers.org/unip...biopax3:standardNameRap guanine nucleotide exchange factor 1lld:biopax3
http://www.phosphosite.org/...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://www.phosphosite.org/...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://pid.nci.nih.gov/biop...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
HTTP://PATHWAYCOMMONS.ORG/P...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://pid.nci.nih.gov/biop...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://pid.nci.nih.gov/biop...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://pid.nci.nih.gov/biop...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://www.reactome.org/bio...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://pid.nci.nih.gov/biop...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://pid.nci.nih.gov/biop...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://www.reactome.org/bio...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://www.reactome.org/bio...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://www.reactome.org/bio...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://pid.nci.nih.gov/biop...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://pid.nci.nih.gov/biop...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://www.reactome.org/bio...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://pid.nci.nih.gov/biop...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://pid.nci.nih.gov/biop...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://pid.nci.nih.gov/biop...biopax3:entityReferencehttp://identifiers.org/unip...lld:biopax3
http://www.pantherdb.org/pa...biopax3:memberEntityReferen...http://identifiers.org/unip...lld:biopax3