http://identifiers.org/unip... | rdf:type | biopax3:ProteinReference | lld:biopax3 |
http://identifiers.org/unip... | biopax3:comment | SEQUENCE 606 AA; 68037 MW; 8C7BC13EB6E01034 CRC64; | lld:biopax3 |
http://identifiers.org/unip... | biopax3:comment | FUNCTION: Required for pseudopod elongation in transformed cells. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. PATHWAY: Protein modification; protein ubiquitination. SUBUNIT: Interacts with NRAP (By similarity). Part of a complex that contains CUL3, RBX1 and KBTBD10. SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, pseudopodium. Cell projection, ruffle. Note=Predominantly cytoplasmic but can co-localize with F-actin at the membrane ruffle-like structures at the tips of transformation- specific pseudopodia. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=Long; IsoId=O60662-1; Sequence=Displayed; Name=Short; IsoId=O60662-2; Sequence=VSP_002819; TISSUE SPECIFICITY: Sarcomeric muscle. PTM: Ubiquitinated and probably targeted for proteasome- independent degradation. SIMILARITY: Contains 1 BTB (POZ) domain. SIMILARITY: Contains 5 Kelch repeats. GENE SYNONYMS:KBTBD10 KRP1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License. | lld:biopax3 |
http://identifiers.org/unip... | biopax3:xref | urn:biopax:UnificationXref:... | lld:biopax3 |
http://identifiers.org/unip... | biopax3:xref | urn:biopax:RelationshipXref... | lld:biopax3 |
http://identifiers.org/unip... | biopax3:xref | urn:biopax:RelationshipXref... | lld:biopax3 |
http://identifiers.org/unip... | biopax3:xref | urn:biopax:RelationshipXref... | lld:biopax3 |
http://identifiers.org/unip... | biopax3:xref | urn:biopax:UnificationXref:... | lld:biopax3 |
http://identifiers.org/unip... | biopax3:displayName | KBTBA_HUMAN | lld:biopax3 |
http://identifiers.org/unip... | biopax3:name | Sarcosin | lld:biopax3 |
http://identifiers.org/unip... | biopax3:name | Kelch-related protein 1 | lld:biopax3 |
http://identifiers.org/unip... | biopax3:name | Kel-like protein 23 | lld:biopax3 |
http://identifiers.org/unip... | biopax3:name | KBTBD10 | lld:biopax3 |
http://identifiers.org/unip... | biopax3:organism | http://identifiers.org/taxo... | lld:biopax3 |
http://identifiers.org/unip... | biopax3:sequence | MDSQRELAEELRLYQSTLLQDGLKDLLDEKKFIDCTLKAGDKSLPCHRLILSACSPYFREYFLSEIDEAKKKEVVLDNVDPAILDLIIKYLYSASIDLNDGNVQDIFALASRFQIPSVFTVCVSYLQKRLAPGNCLAILRLGLLLDCPRLAISAREFVSDRFVQICKEEDFMQLSPQELISVISNDSLNVEKEEAVFEAVMKWVRTDKENRVKNLSEVFDCIRFRLMTEKYFKDHVEKDDIIKSNPDLQKKIKVLKDAFAGKLPEPSKNAAKTGAGEVNGDVGDEDLLPGYLNDIPRHGMFVKDLILLVNDTAAVAYDPTENECYLTALAEQIPRNHSSIVTQQNQIYVVGGLYVDEENKDQPLQSYFFQLDSIASEWVGLPPLPSARCLFGLGEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWNEVKKLPIKVYGHNVISHKGMIYCLGGKTDDKKCTNRVFIFNPKKGDWKDLAPMKIPRSMFGVAVHKGKIVIAGGVTEDGLSASVEAFDLTTNKWDVMTEFPQERSSISLVSLAGSLYAIGGFAMIQLESKEFAPTEVNDIWKYEDDKKEWAGMLKEIRYASGASCLATRLNLFKLSKL | lld:biopax3 |
http://identifiers.org/unip... | biopax3:standardName | Kelch repeat and BTB domain-containing protein 10 | lld:biopax3 |
HTTP://PATHWAYCOMMONS.ORG/P... | biopax3:entityReference | http://identifiers.org/unip... | lld:biopax3 |