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rdf:type |
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calbc:hasCorrelation |
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skos:exactMatch |
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skos:definition |
MSH: Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.,CSP: genes whose loss or deactivation leads to neoplastic transformation; compare with ONCOGENE and PROTOONCOGENE.,NCI: A type of gene that makes a protein called a tumor suppressor protein that helps control cell growth. Mutations (changes in DNA) in antioncogenes may lead to cancer.,NCI: Tumor Suppressor Genes encode proteins whose functions inhibit expression of tumorigenic phenotypes by holding cellular proliferation in check. When inactivated or lost, a barrier to normal proliferation is removed and deregulated growth is possible. (NCI)
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skos:inScheme |
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skos:broader |
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skos:narrower |
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skos-xl:prefLabel |
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skos-xl:altLabel |
umls-label:A0024625,
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umls:relation |
http://linkedlifedata.com/resource/umls/relation/R28412183,
http://linkedlifedata.com/resource/umls/relation/R28412195,
http://linkedlifedata.com/resource/umls/relation/R28485307,
http://linkedlifedata.com/resource/umls/relation/R28485308,
http://linkedlifedata.com/resource/umls/relation/R28412434,
http://linkedlifedata.com/resource/umls/relation/R28485491,
http://linkedlifedata.com/resource/umls/relation/R28421249,
http://linkedlifedata.com/resource/umls/relation/R28494620,
http://linkedlifedata.com/resource/umls/relation/R28423915,
http://linkedlifedata.com/resource/umls/relation/R28423950,
http://linkedlifedata.com/resource/umls/relation/R28423951,
http://linkedlifedata.com/resource/umls/relation/R28424008,
http://linkedlifedata.com/resource/umls/relation/R28497887,
http://linkedlifedata.com/resource/umls/relation/R28497888,
http://linkedlifedata.com/resource/umls/relation/R28497889,
http://linkedlifedata.com/resource/umls/relation/R28497890,
http://linkedlifedata.com/resource/umls/relation/R28424013,
http://linkedlifedata.com/resource/umls/relation/R28497946,
http://linkedlifedata.com/resource/umls/relation/R28497947,
http://linkedlifedata.com/resource/umls/relation/R31980434,
http://linkedlifedata.com/resource/umls/relation/R32174219,
http://linkedlifedata.com/resource/umls/relation/R120521079,
http://linkedlifedata.com/resource/umls/relation/R120521080,
http://linkedlifedata.com/resource/umls/relation/R120521078,
http://linkedlifedata.com/resource/umls/relation/R120521081,
http://linkedlifedata.com/resource/umls/relation/R71071843,
http://linkedlifedata.com/resource/umls/relation/R71060446
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