umls-concept:C2348503 | skos:definition | NCI: Human FOXO3 wild-type allele is located in the vicinity of 6q21 and is approximately 121 kb in length. This allele, which encodes forkhead box protein O3A, plays a role in the activation of both transcription by RNA polymerase II and apoptosis that is induced by oxidative stress. | lld:umls |