| umls-concept:C1956346 | skos:definition | MSH: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.,MEDLINEPLUS: <p>Coronary artery disease (CAD) is the most common type of heart disease. It is the leading cause of death in the United States in both men and women.</p><p>CAD happens when the arteries that supply blood to heart muscle become hardened and narrowed. This is due to the buildup of <a href='http://www.nlm.nih.gov/medlineplus/cholesterol.html'>cholesterol</a> and other material, called plaque, on their inner walls. This buildup is called <a href='http://www.nlm.nih.gov/medlineplus/atherosclerosis.html'>atherosclerosis</a>. As it grows, less blood can flow through the arteries. As a result, the heart muscle can't get the blood or oxygen it needs. This can lead to chest pain (<a href='http://www.nlm.nih.gov/medlineplus/angina.html'>angina</a>) or a <a href='http://www.nlm.nih.gov/medlineplus/heartattack.html'>heart attack</a>. Most heart attacks happen when a | lld:umls |
