| umls-concept:C1621525 | skos:definition | GO: A protein complex that forms part of the inner centromere, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human. [GOC:vw, PMID:12719471, PMID:15897182] | lld:umls |
