| umls-concept:C1512792 | skos:definition | NCI: Any substance that inhibits inosine monophosphate dehydrogenase, an enzyme that catalyzes the conversion of inosine monophosphate to xanthosine monophosphate, the rate-limiting step in the de novo biosynthesis of guanine nucleotides. Inhibition of inosine monophosphate dehydrogenase can lead to inhibition of cell proliferation. | lld:umls |
