| umls-concept:C0383327 | skos:definition | MSH: A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity.,CSP: cytokine which resembles interleukin 1 structurally and interleukin 12 functionally; enhances cytotoxic activity of NK cells and CTLs; appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity.,NCI: Cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK cells and CTLs, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity.,NCI: IL18 is a cytokine that resembles IL1 structurally and IL12 functionally. It is expressed in Kupffer cells and in activated macrophages and augments the cytotoxic activity of NK cells and CTLs. By increasing expression of vascular cell adhesion molecule 1, as well as adherence of melanoma cells to capillary e | lld:umls |
