| umls-concept:C0242606 | skos:definition | MSH: A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).,CSP: damage to biological tissues caused by superoxide and other free radicals generated as a result of intoxication, antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; do not confuse with HYPOXIA or HYPEROXIA.,NCI: A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products. The damage to biological tissues is caused by superoxide and other free radicals generated by many factors, including exposure to alcohol, medications, trauma, cold, toxins, and radiation or by antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; not synonymous with hy | lld:umls |
