| umls-concept:C0221355 | skos:definition | MSH: A congenital abnormality in which the occipitofrontal circumference is greater than two standard deviations above the mean for a given age. It is associated with HYDROCEPHALUS; SUBDURAL EFFUSION; ARACHNOID CYSTS; or is part of a genetic condition (e.g., ALEXANDER DISEASE; SOTOS SYNDROME).,NCI: An abnormally large head. Causes include hydrocephalus, enlarged brain, and cranial hyperostosis. | lld:umls |
