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skos:definition |
MSH: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.,CSP: excess in the blood of urea, creatinine and other nitrogenous end products of protein and aminoacid metabolism; also, the constellation of signs and symptoms of chronic renal failure.
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