umls-concept:C0036572 | skos:definition | AIR: WHAT: Seizure. Seizure: a paroxysmal transient disturbance of brain function that may be manifested as episodic impairment or loss of consciousness, abnormal motor phenomena, psychic or sensory disturbance or perturbation of the autonomic brain electrical activity. WHY: Seizures may occur in systemic lupus erythematosus or in necrotizing vasculitides such as polyarteritis, eosinophilic granulomatous vasculitis, aortic arch arteritis, or rheumatoid arteritis. HOW: A seizure probably exists when there are generalized convulsions or focal motor/sensory phenomenon. GENERALIZED CONVULSIONS may be preceded by an aura but usually have a sudden loss of consciousness with generalized muscle rigidity then generalized muscle activity. They may have incontinence of urine or feces or laceration of the tongue or buccal mucosa. This usually is followed by flaccidity, drowsiness, or complaints of a headache or sore muscles. FOCAL MOTOR/SENSORY PHENOMENON may precede generalized convulsions but may be tonic or clonic mus | lld:umls |