| umls-concept:C0034013 | skos:definition | MSH: Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE.,CSP: unusually early sexual maturity.,NCI: Unusually early sexual development or maturity; premature puberty.,NCI: Unusually early sexual maturity.,NCI: A disorder characterized by unusually early development of secondary sexual features; the onset of sexual maturation begins usually before age 8 for girls and before age 9 for boys. | lld:umls |
