| umls-concept:C0033975 | skos:definition | AIR: WHAT: Psychosis. Psychosis: a loss of contact with reality, a thought disorder, or a change of personality or behavior often associated with delusions, illusions, or hallucinations. WHY: Psychosis may occur in systemic lupus erythematosus, mixed connective tissue disease, or with the administration of steroids, cimetadine (Tagemet), or reserpine. HOW: A psychosis probably exists if a patient demonstrates one or more of the following major criteria: MAJOR CRITERIA LOSS OF CONTACT WITH REALITY -- evidenced by the misinterpretation of the environment as hostile when friendly or vice versa, generally causing bizarre responses to normal and usual environmental stimuli. THOUGHT DISTURBANCE -- evidenced by incoherence, marked illogical content, marked loose associations, or patient's admission of mental confusion and abnormal rate of mental activity. PERSONALITY/BEHAVIOR CHANGES -- characterized by rapid onset and reversals of previous behavior patterns, often observed by reliable family member or friend. The d | lld:umls |
