| umls-concept:C0026820 | skos:definition | MSH: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.,CSP: process leading to shortening and/or development of tension in muscle tissue; occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.,GO: OBSOLETE (was not defined before being made obsolete). [GOC:mah],GO: A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. [GOC:ef, GOC:mtg_muscle, ISBN:0198506732],NCI: The process where thick (myosin) and thin (actin) filaments slide against each other to produce a shortening or tensing of the muscle cell or fiber. | lld:umls |
