| umls-concept:C0024591 | skos:definition | MSH: Rapid and excessive rise of temperature accompanied by muscular rigidity following general anesthesia.,CSP: usually inherited reaction to general anesthesia manifested as a sudden, rapid rise in temperature, hypermetabolism, and skeletal muscle rigidity; mutation is in the calcium release channel of skeletal muscle sarcoplasmic reticulum.,NCI: A rare disorder characterized by rapid rise of the body temperature, accompanied by rhabdomyolysis and, if untreated, by collapse and death. It occurs in susceptible individuals who receive certain drugs for general anesthesia, gas anesthetics, or succinylcholine. It may be inherited in an autosomal dominant pattern. | lld:umls |
