umls-concept:C0023462 | skos:definition | MSH: An acute myeloid leukemia in which 20-30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. MYELOFIBROSIS or increased bone marrow RETICULIN is common.,NCI: A progressive, proliferative disease of blood cells, originating from immature megakaryocytes.,NCI: An acute myeloid leukemia in which at least 50% of the blasts are of megakaryocytic lineage. The prognosis is usually poor. (WHO, 2001) | lld:umls |