| umls-concept:C0020522 | skos:definition | MSH: An increased reactivity to specific antigens mediated not by antibodies but by cells.,CSP: increased reactivity to specific antigens mediated not by antibodies but by cells.,NCI: An inflammatory response that develops 24 to 72 hours after exposure to an antigen that the immune system recognizes as foreign. This type of immune response involves mainly T cells rather than antibodies (which are made by B cells).,GO: An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation. [GOC:add, ISBN:0781735149],NCI: Delayed hypersensitivity reaction (DTH) - type IV reaction, an inflammatory response that develops 24 to 72 hours after exposure to an antigen that the immune system recognizes as foreign. DTH is mediated by T cells rather than by antibodies. Th1 cells produce interferon gamma, interleukin (IL)-2, and tumor necrosis factor-beta and promote a cell-mediated immune response. | lld:umls |
