| umls-concept:C0018824 | skos:definition | MSH: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).,CSP: condition in which there is a deviation from or interruption of the normal functioning of heart valves.,NCI: Any heart disorder characterized by a defect in valve structure or function.,MEDLINEPLUS: <p>Your heart has four valves. Normally, these valves open to let blood flow through or out of your heart, and then shut to keep it from flowing backward. But sometimes they don't work properly. What can happen?</p><ul><li> Blood can leak back through the valve in the wrong direction, which is called regurgitation</li><li> One of the valves, the mitral valve, sometimes has "floppy" flaps and doesn't close tightly. This is called <a href='http://www.nlm.nih.gov/medlineplus/mitralvalveprolapse.html'>mitral valve prolapse</a>, and it's one of the most common heart valve conditions. Sometimes it causes regurgitation</li><li> When the valve doesn't open enough, w | lld:umls |
