| umls-concept:C0016904 | skos:definition | MSH: The most common inhibitory neurotransmitter in the central nervous system.,NCI: A naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity. Gamma-aminobutyric acid (GABA), converted from the principal excitatory neurotransmitter glutamate in the brain, plays a role in regulating neuronal excitability by binding to its receptors, GABA-A and GABA-B, and thereby causing ion channel opening, hyperpolarization and eventually inhibition of neurotransmission.,CHV: a chemical substance released by nerves in the brain,CHV: a chemical substance released by nerves in the brain,CHV: a chemical substance released by nerves in the brain,CHV: a chemical substance released by nerves in the brain | lld:umls |
